Our
Team

Our interdisciplinary team comprises of experts across medicinal chemistry, cheminformatics, computational biology and machine learning

Francesco Trozzi, PhD
Computational Chemistry

Dr. Francesco Trozzi, PhD, is a part of Harmonic Discovery's computational chemistry team. Dr. Trozzi received his PhD from SMU where he studied the mechanism of protein allostery in LOV Domains and ACE2 PD via molecular dynamics and machine learning.

Anna Cichońska, PhD
Director of Data Science and Head of European Operations

Dr. Anna Cichońska, PhD, is Harmonic Discovery's Director of Data Science and Head of European Operations. Dr. Cichońska completed her PhD at Aalto University and the Finnish Institute for Molecular Medicine in computational biology and machine learning. She is an expert in the development of machine learning models to predict kinase-ligand interactions.

Ravi Rajagopalan, PhD
VP of Drug Discovery & Development

Dr. Ravi Rajagopalan, PhD is VP of Drug Discovery & Development at Harmonic Discovery. Dr. Rajagopalan is a biology, drug discovery and development leader with 20 years of collective experience in SF bay area biotechs (Celera Genomics, InterMune and Blade Therapeutics). Ravi has directly contributed to 5 clinical candidates and 3 marketed drugs.

Marcel Patek, PhD
Founder & Chief Scientific Officer

Dr. Marcel Patek, PhD, is a co-founder and CSO of Harmonic Discovery. Dr. Patek is an industry veteran with over 25+ years of experience in drug discovery. Previously he was the Director of Chemistry at Sanofi and the Vice President of chemistry at ICAGEN.

Navriti Sahni, PhD
Medicinal and Computational Chemistry

Dr. Navriti Sahni, PhD, is a part of the Medicinal and Computational Chemistry team at Harmonic Discovery. Dr. Sahni completed her PhD at Punjabi University and has extensive expertise in designing multi-targeted kinase therapeutics.

Guru Ravikumar, PhD
Director of Chemical Informatics

Dr. Guru Ravikumar, PhD, is Harmonic Discovery's Director of Chemical Informatics. Dr. Ravikumar completed his PhD at the University of Helsinki where he developed several computational chemogenomic approaches to study the polypharmacology of kinase inhibitors.

Rayees Rahman, PhD
Founder & Chief Executive Officer

Dr. Rayees Rahman, PhD, is a co-founder and CEO of Harmonic Discovery. Dr. Rahman completed his PhD at the Icahn School of Medicine at Mount Sinai where he developed machine learning approaches to characterize the 3D structure of protein kinases and their inhibitors.

Jason Lee, MD
Founder & Chief Operating Officer

Dr. Jason Lee, MD, is a co-founder and COO of Harmonic Discovery. Dr. Lee completed his medical training at the Icahn School of Medicine at Mount Sinai. Previously he was a life science investor at OrbiMed, and performed business development duties at Pacira Pharmaceuticals.

Ryan Theisen, PhD
Machine Learning

Ryan Theisen is part of the Machine Learning team at Harmonic Discovery. He completed his PhD in Theoretical Machine Learning at the University of California, Berkeley.

Board of Directors & Scientific Advisory Board

Andreas Bender, PhD
Scientific Advisory Board

Dr. Andreas Bender is leading expert in medicinal chemistry and cheminformatics. Dr. Bender is a Professor of Molecular Informatics at Cambridge University and CSO of Terra Lumina. Previously he was Associate Director of Computational ADME and Safety at AstraZeneca and at co-founder of HealX.

Olivier Elemento, PhD
Scientific Advisory Board

Dr. Oliver Elemento, PhD, is an expert in biomedical data science and systems biology for drug discovery. Dr. Elemento is a Professor of Physiology and Biophysics at Weill Cornell Medicine and the Director of the Englander Institute for Precision Medicine. He is also the founder of venture-backed startups such as Volastra Therapeutics and Onethree Biotech.

Omar Abdel-Wahab, MD
Scientific Advisory Board

Dr. Omar Abdel-Wahab, MD, is an oncologist and expert in blood and solid tumors. Dr. Abdel Wahab is the Chair of Molecular Pharmacology at the Sloan Kettering Institute and Director, MSK Center for Hematologic Malignancies.

Tero Aittokallio, PhD
Scientific Advisory Board

Dr. Tero Aittokallio, PhD, is an expert in statistical and predictive drug response modeling. He is professor and group leader at the Institute for Cancer Research at Oslo University Hospital and a group leader at the Institute for Molecular Medicine Finland.

John Mascarenhas, MD
Scientific Advisory Board

Dr. John Mascarenhas is a Professor of Medicine at the Icahn School of Medicine, where he directs the Adult Leukemia Program. He has deep experience in Myeloproliferative neoplasms, specifically in Myelofibrosis.

Stephen Oh, MD PhD
Scientific Advisory Board

Dr. Stephen Oh is an Associate Professor of Medicine in the Division of Hematology at Washington University School of Medicine. His research focuses on myeloproliferative neoplasms (MPNs) and his group investigates fundamental mechanisms driving the initiation, development and progression of MPNs.

Joel Dudley, PhD
Board of Directors

Dr. Joel Dudley is an expert in biomedical data science, computational biology and machine learning. He currently is a partner at Innovation Endeavors. Previously he was Chief Scientific Officer at Tempus Labs, and executive Vice President and Associate Professor at the Mount Sinai School of Medicine. He was also the co-founder of companies such as Onegevity Health and Numedii.

Harmonic Discovery Student Scientists

Oanh Tran
Biophysics

Tran is a PhD student in Biophysics at University of California Irvine

David Allegakoen
MD/PhD student

David Allegakoen is an MD/PhD student at Georgetown University

Harmonic Alumni

Annalise Schweickart
Computational prediction of kinase anti-targets

Annalise Schweickart is a PhD student at the Tri-Institutional Computational Biology and Medicine Program at Weill Cornell Medical College.

Carmen Al Masri
Kinase structural bioinformatics & ML

Carmen Al-Masri is a PhD student in Computational Chemistry at University of California Irvine.

Colin Small
kinase chemical space library

Colin Small is a Masters student in Bioinformatics at Brown University.

Eric Bach, PhD
Kinase inhibitor chemical similarity networks

Dr. Eric Bach, PhD. Completed his PhD at Aalto University in Machine Learning.

Katalina Biondi
generative modeling for kinase inhibitor design

Katalina Biondi is a PhD student in Machine Learning the University of Southern Florida.

Yajas Shah, PhD
prediction of synergistic kinase co-targets

Yajas Shah is a PhD student in Computational and Systems Biology at Weill Cornell Medical College.

Yohana Ghebrechristos, PhD
kinase-driven cancer biology

Dr. Yohana Ghebrechristos, PhD completed her PhD in Cancer Biology at New York University.

Jason Lin
Common Scaffold Visualizer

Jason Lin is a BS student in Chemical Engineering at the University of Michigan Ann Arbor

Michael Moret, PhD
Machine Learning

Dr. Michael Moret, PhD completed his PhD in molecular machine learning at ETH Zurich. He is currently a post-doc at the George Church Lab at Harvard

Steven Pak
Computational Chemistry

Steven Pak is a PhD student in computational chemistry at Stony Brook University

Ankita Dutta
Computational Chemistry

Ankita is a PhD student in computational chemistry at City University of New York

Ryan Park
Undergraduate Student

Ryan Park is an undergraduate student at Stanford University

Prateek Adurty
Undergraduate Student

Prateek Adurty is an undergraduate student at the University of Pennsylvania

Tian Wang
Computational Biology

Tian Wang is a PhD student in computational biology at the University of Helsinki and Aalto University,

Juhi Somani
Bioinformatics

Juhi was a Bioinformatics scientist at Harmonic Discovery. She completed her PhD at the University of Helsinki